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蛋白质多态现象的研究及其应用

周虞灿   

  1. 中国科学院西北高原生物研究所
  • 出版日期:2011-11-22 发布日期:2011-11-22

STUDIES AND APPLICATIONS OF PROTEIN POLYMORPHISM

ZHOU Yucan   

  1. Northwest Plateau Institute of Biology, Academia Sinica
  • Online:2011-11-22 Published:2011-11-22

摘要: 蛋白质多态现象是生物界比较普遍的现象,有其深刻的生物学意义。蛋白质多态现象的研究是从Smithies(1955)以淀粉凝胶为载体电泳分离血清蛋白、乳蛋白以及蛋清蛋白的成功才得以发展的。

Abstract: In the last two decade it has witnessed the growth of a new interdisciplinary knowledge which is termed "protein polymorphism",, It is concerned with biochemistry and genetics, and have been extensively researched and applied in the branches of biology, regarding as a useful tool of biology. However, a systematic and special introduction of basic principles of this subject is not found yet. This paper deals with the fundamental know-ledge of protein polymorphism. The definition of the polymorphism, electrophoretic method and questions worthy of note,the use of allelic concept in the analysis of electrophoretic pattern, the calculation of gene and genotype frequencies, and the examples of application of protein polymorphism to population genetics, taxonomy, zootechnics and diagnostic enzymology are included in this paper. And some are bescribed in detail.