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长爪沙鼠产后发育中线粒体产能

李庆芬, 黄晨西, 孙儒泳, 蔡兵   

  1. 北京师范大学生物系
  • 出版日期:2006-07-26 发布日期:2007-09-14

A STUDY OF MITOCHONDRIA-PRODUCED ENERGY DURING POSTNATAL DEVELOPMENT IN CLAWED JIRD, MERIONES UNGUICULATUS

LI Qingfen, HUANG Chenxi, SUN Ruyong, CAI Bing   

  • Online:2006-07-26 Published:2007-09-14

摘要: 本文通过产后1日龄到3O日龄长爪沙鼠肝脏和棕色脂肪组织的线粒体研究揭示,肝线粒体在出生后的呼吸速率、氧化磷酸化作用以及细胞色素氧化酶活力均达到恒定水平。肝线粒体蛋白质量随胎后发育日龄而增加,直至2O日龄左右,琥珀酸氧化酶活力在此时也增加到近于恒定,因此肝线粒体产能发育随日龄增长到2O日龄右。这可能是长爪沙鼠体温调节发育的细胞机制之一。从棕色脂肪线粒体的细胞色素氧化酶和琥珀酸氧化酶活力的变化,显示棕色脂肪组织在长爪沙鼠新生幼仔阶段产热中所起的重要作用。

关键词: 长爪沙鼠, 产后发育, 肝线粒体, 棕色脂肪组织

Abstract: The present paper has showed that the levels of respiratory rate,oxidative phosphorylation and cytochrome oxidase activity of liver mitochondrla at first day after birth in Clawed jird were the same as those of 30 days old. Protein contents of the liver mitoehondria increased with developmental stage by about 20 days and mitochondria -produced energy was enhanced with growth by that time. Thismightbeone of the cellular mechanism of therrnoregulation in Clawed jird. The changes of cy ochrome oxidase activlty and succinate oxidase activity of brown adipose tissue mitochondrie displayed that brown adipose tissue played an important role in thermoregulation of neonatal.

Key words: Clawed jird Meriones unguiculafus postnatal development 1iver mitochondria、brown adipose tissue。