关键词: 高原鼠兔, 性腺, 雌二醇, 睾丸指数, 低氧

Abstract: 　Effects of hypoxia on the sex gland of male plateau pika (Ochotona curzoniae) and rat were carried out by simulated different altitude (5 000 m and 7 000 m ) in the well-ventilated hypobaric pressure chamber for 24 h and 7 d, comparing with that at 2300m of altitude. The experiment shows: the plasmaest rogen (E₂) level of male plateau pika increased obviously at 5 000m and 7 000m altitude for 24 h and 7 d. The ratio of testis to body weigh ts inplateau pika was no change at 5000 m of alt itude but decreased at 7000m for hypoxia 7d, by contrary, that of rat increased significantly at the same condition. The testicular histomorphology of plateau pika kep tunchangeable at all altitude simulated for 7d. These suggest that E₂may play a role in an adaptation to hypoxia in Ochotona curzoniae.

Key words: Plateau pika (Ochotona curzoniae), Sexual gland, Estrogen E2, Ratio of testis/body weight, Hypoxia