关键词: 棕色田鼠 主嗅球 副嗅球 FOS 尿液

Abstract: In many vertebrates,odor cues from urine and anal and genital sebaceous gland secretions play important roles in heterosexual partner selection,reproductive success,recognition of strain and gender,etc. Detection,transduction,and processing of these odors are accomplished through either the main olfactory system or the accessory olfactory system. Many studies have indicated that pheromones induced the activities of neurons in the Accessory olfactory bulb (AOB),and nonsocial odors activated those of main olfactory bulb (MOB) In our study,neuronal activation in the MOB and AOB of the mandarin voles (Microtus mandarinus)was investigated using Fos-immunoreactivity (FOS-ir)as an indicator following exposure to the urine of same or opposite sex Mandarin voles exposed to urine of the same and opposite sex produced significantly more Fos-ir neurons in the accessory olfactory bulb (AOB)compared with voles in the control group;Voles exposed to urine of the opposite sex had more Fos-ir neurons in the AOB than voles exposed to urine from same sex,suggesting that AOB participated in sex discrimination of mandarin voles Furthermore,mandarin voles exposed to urine of the same and opposite sex produced more or significantly more Fos-ir neurons in the MOB than did control voles Voles exposed to urine of the opposite sex had more Fos-ir neurons in the MOB than did voles exposed to urine from the same sex,indicating that MOB also participated in sex discrimination of mandarin voles Our result suggests that both AOB and MOB were involved in sex discrimination by chemosensory signals in urine.

Key words: Accessory olfactory bulb (AOB) FOS Main olfactory bulb (MOB) Microtus mandarinus Urine