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大熊猫胃肠道内分泌细胞分布型的研究

杨贵波, 陈茂生, 邓泽沛, 王平   

  1. 北京大学生命科学学院,北京
  • 出版日期:2006-07-29 发布日期:2008-07-07

THE DISTRIBUTION 0F END0CRINE CELLS IN THE GUT MUC0SA 0F THE GIANT PANDA

YANG Guibo, CHEN Maosheng, DENG Zepei, WANG Ping   

  • Online:2006-07-29 Published:2008-07-07

摘要: 本文用PAP法对3只大熊猫胃底,幽门腺区,十二指肠、空肠,回肠、结肠和直肠的五羟色胺,生长抑素、胃素、胆囊收缩素 神经降压素,胃动素,抑胃多肽、胰高血糖素,血管活性肠肽和内啡肽的IR细胞进行了研究。结果表明,大熊猫胃肠到粘膜上皮中具有前八种IR细胞。对7年龄个体胃肠各段相对数量的比较和各段内分布情况的观察结果表明,除五羟色胺IR细胞在空肠分布较多外,大多数种类的IR细胞集中分市于幽门区和十二指肠;幽门区的IR细胞主要集中在腺颈部附近。与已有的研究比较,大熊猫胃肠道中五羟色胺,胆囊收缩素、胰高血糖素、生长抑素IR蛔胞的分布型较为特殊,可能与其特殊的食性和分类地位有关。

关键词: 大熊猫, 胃肠道, 内分泌细胞, 分布

Abstract: Endocrine cells containing 5-hydroxytryptamine,somatostetln, gastrin, cholecystokinin , neurotensin, motilin, gastric inhibitory polypeptide, glucagon,vasoactive intestinal peptide,and endorphin in the mucosa of the fundus,pylorusduodenum,jejunum,ileum,colon,and rectum of 3 giant pandas were studied by PAP method to gain an insight into the adaptive characteristics for the special feeding habit.The former 8 kinds of endocrine cells were detected in the mucose of the 75 day-old and7 year-old giant pandas.Quantitative analyses of inter-and intra-segmental differences in the frequency of occurrence of each kind of the endocrine cells in the stomach and small intestine 0f the 7 year-old individual showed that:5-HT immunoreaetive cells occur most frequently in the jejunum, which has not been observed in the other mammals. Cholecystokinin、gastrin、somatostatin immunoreaetive cells occur most frequently in the pyloric antrum,while motilin immunoreactive cells occur most frequently in the duodenum , gastric inhibitory peptide、neurotensin、glucagon immunoreaetive cells occur most frequently in the ileum .Endocrine cells distribute principally in the lower two-thirds of the fundic gland,near the neck portion of the pyloric gland,and in the crypts of Lieber-kuhn's gland with the exception of 57% of neurotensin immunoreactive cells distribute in the mucosa of the villus. These results indicate specific patterns of distribution of the endocrine cells in the mucosa of the giant panda, which might be related both to their specific feeding habit and their taxonomicposition.

Key words: Giant Panda (Ailuropoda melanoleuca), Gastrointestinal tract:Endocrine cel1, Distribution