Understanding wildlife movement and space use is essential for designing effective conservation management strategies. Many top predators, such as wolves (Canis lupus), are elusive and difficult to study. We captured and placed GPS collars on free-ranging male and female grey wolves Canis lupus in the Mount Kalamaili Ungulate Nature Reserve in January and November 2014. We recorded 513 active locations for the adult male and 870 locations for the adult female. Minimum Convex Polygon (MCP) estimated home range sizes of 1947km2 and 3728km2 for the male and female wolf, respectively. On a global scale these preliminary results suggest that wolves persisting in Mount Kalamaili Ungulate Nature Reserve may have the largest home range sizes of any wolf population in the world. Locally, it may demonstrate the need for large-scale management of this key protected landscape as both male and female wolves require vast areas to survive. Further research is urgently required to expand the sample size of collared wolves to increase confidence in home range estimates and to examine any ecological or human-induced effects on habitat selection for this important population of wolves.