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ZHANG Zhibin
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摘要: 小家属、欧洲兔和红狐是在澳洲危害最为严重的3种有害脊椎动物。1992-1999年间,澳大利亚共投资了5000多万澳元用于研究防止小家鼠、欧洲兔和红狐的不育疫苗,有关免疫不育技术的研究已有很大进展,主要体现在重组病毒性不育疫苗已接近实用化。有关不育控制的生态学理论研究也有了很大的进展,初步确定了合适的不育水平,这为不育疫苗生态风险评估和大田释放试验工作奠定了基础。相比之下,非病毒或细菌性的、口服性的毒饵疫苗的研制尚无大的突破,但这仍然是研究的重点。
关键词: 有害脊椎动物, 免疫不育, 不育控制, 澳大利亚
Abstract: House mice, European rabbit and red fox are the three major vertabrate pests in Australia. From 1992 to 1999, Australia Cooperative Research Center sponsored 50 million Australia dollars for developing immuno-contraceptives for managing these three pests. In contract with the research in 1990's, much advance have been achieved by this program, e.g. the recombined immuno-contraceptive virus vaccine(rMCMV-ZP3 and ECTV-ZP3)for controlling house mice. Much progress have been also made in ecological aspects on the fertility control which is essential for assessing ecological risk and field release of vaccines. However, no breakthrough has been made in developing oral and non-GMOs vaccines. The oral delivery system is still the active research area for the immuno-contraception control.
Key words: vertebrate pest, Immuno-contraception, Fertility control, Australia
. 澳大利亚在应用免疫不育技术防治有害脊椎动物研究上的最新发展[J]. .
ZHANG Zhibin. ADVANCE OF IMMUNO-CONTRACEPTION IN VERTEBRATE PEST MANAGEMENT IN AUSTRALIA[J]. .
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https://www.mammal.cn/CN/Y2000/V20/I2/130