关键词: 大仓鼠, 雌二醇, 胁腺, 形态, 化学

Abstract: The effects of estradiol on the size and secretion chemistry of flank glands in female ratlike hamsters (Cricetulus triton) were studied. By surgical procedure and hormone replacement，three groups of hamsters being different in reproductive status were formed，which were ovariectomized (OF),intact (IF) and overiectomized plus estradiol cap sides females(OEF).From OF to OEF, blood levels of estradiol determined by radioimmunoassay was getting higher (P<0.01),while the weight, length, width and thickness of flank glands were getting less(P<0.05 or P<0.01) by groups. Gas chromatography was usedto measure the differences in flank gland secretions among three groups of hamsters.It was found that there were qualitative and quantitative changes among chemical compounds of flank gland secretions of three groups. Some compounds have a decrease in quantity from OF to 0EF，and less and less compounds were detected from OF to OEF.The results evidenced that estradiol can inhibit both size and secretion activity of flank glands.

Key words: Ratlike hamster(Cricetulus triton), Estradiol, Flank gland, Morphology Chemistry