ACTA THERIOLOGICA SINICA ›› 2014, Vol. 34 ›› Issue (4): 406-.
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ZHANG Chunyan,HOU Tiande,XU Dengcui,DING Weigang,ZHANG Huiying
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张春燕 侯天德 徐登翠 丁卫刚 张慧瑛
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Abstract: Indices such as many kinds of blood inorganic ions and urea nitrogen were measured in this paper. The histological structure of kidney in Vormela peregusna was examined by using biological microscopy. The expression of Aquaporin1,2 (AQP1,2)was tested using immunohistochemical and stereological quantitative methods,and the expression intensity of Aquaporin1,2 (AQP1,2)was analyzed by using image pro-plus (IPP)image software. The results show that the concentration of K+ ,Na + ,Cl- ,Ca 2 + in serum of Vormela peregusna is higher than that in rat,however P 3+ is lower than that in rat.Creatinine,glucose and total cholesterol in serum also are higher than those in rat. Urea nitrogen is much higher than that in rat,and may be related to living in the Minqing Gansu desert and eating rodents that have high protein content. The degree of concentration of urine is high because the ratio of medulla and cortex is 3. 65∶ 1 and medulla is wide. AQP1 positive cells were expressed in the epithelium of proximal the convoluted tubule and thin segments of the medullary loop,and AQP2 was mainly expressed in epithelial cells of collecting ducts. Thus,AQP1,2 may play an important role water reabsorption by the kidney and the concentration of urine,which regulated by the water balance of kidney.
Key words: Immunohistochemistry, The histological structure of kidney, The expression of aquaporin 1,2 protein, Vormela peregusna
关键词: 虎鼬, 血清指标, 肾组织结构, 水通道蛋白1,2 的表达, 免疫组织化学
ZHANG Chunyan, HOU Tiande, XU Dengcui, DING Weigang, ZHANG Huiying. Light microscope structure of Vormela peregusna kidney and expression of AQP1,2 in kidney[J]. ACTA THERIOLOGICA SINICA, 2014, 34(4): 406-.
张春燕 侯天德 徐登翠 丁卫刚 张慧瑛. 虎鼬肾组织结构及水通道蛋白1,2 的表达[J]. 兽类学报, 2014, 34(4): 406-.
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https://www.mammal.cn/EN/Y2014/V34/I4/406