Abstract: The lesser slow Loris (Nycticebus pygmaeus) is a small prosimiam living Vietnam Laos, and the south part of Yunnan Province in China. Its characteristics of thermoregulation and cellular respiration had not been reported. In order to understand the animal’s feathers of thermoregulation its cellular mechanisms, and adaptation to living environment, the characteristics of thermogenesis in individual level including nonshivering thermogenesis(NST_MAX), the respiration of mitochondria in liver, and the activities of cytochrome C oxidase (COX) and a-glycerophophate oxidase (α-PGO) were measured. The results obtained mainly were as follows: The NST_MAX, was measured at 15 and 30 °C ambient temperatures by injecting noradrenaline( NE) . The NST_MAX at 15 °C , 1.96 ±0.08 ml 0₂/g.h(N= 10), was significantly higher than that at 30°C, 1.56 ± 0.14 ml 0₂/g. h (N=10), NSTRMR 100%, 230.4% (at 15 °C) and 291.1% was as the same that. But the NST-RMR) at 15 °C, 1.11 ±0.13, was equal to that at 30 °C, 1.07±0.14. At the same time, the shivering was observed in experiment and strengthened with declining ambient temperature. Thus, the NST-RMR NST at 15 C might involved shivering thermogenesis. But the RMR 100% of the lesser slow loris was also higher than that of other mammals, it could related to nocturnal behavioral pattern. The weight of BAT, 0.83+0.12 g (N=9), BAT/BW ×100% was 0.42%, was larger than that of other primates but the BAT/BW ×100% was lower than that of Tupaia belangeri, 0.51%. At the same time, the total and mitchondrial protein content of BAT were 23 .3 ± 4.85 mg/g) and 11.2 ±1 .01 Eng/g) respectively and the former was equal to that of T. belangeri during winter approximately but the later was remarkably lower than that of T. belangeri. The activities of COX andα-PGO were 455.3 ±30.1 (ng O atom/mg mit protein. min) and 36 .8 ± 5 .8 (ng O atom/mg total protein. min) separately. These results shown that the higher level of NST_MAX -RMR /RMR ×100% in the animal related to that the activities of in BAT were higher in the animal. The total and mitchondrial protein content were 37.41 ±5.25and 18.0 ±0.95( mg/g)in liver; the mitchondrial state IV and III respiration were separately 10.0 ±1 .3 and 34 .5± 2.7 (ng O/mg mit. protein mm), and the activity of COX 0.5 ±5.8ng atom 0/mg mit protein. min) was only 1/3, 1/2 of T. belangeri( 80.89 ±5.56); the activity of α-PGO was 10.44± 1.04(ng atom O/mg total protein. min) was also only 1/5- 1/4 of T. belangeri. For this reason it was main factor that the oxidative activity of the liver mitochondria was lower.
Conclusion: There was general characteristics of thermoregulation of prosimiams , including lower NST_MAX, in the lesser slow loris, but the ratio of NST was higher than that of other primates and which was related to the oxidation of BAT was strengthened. At the same time, it was main reason that the activity of oxidation in liver mitochondria made the level of BMR decrease.

Key words: lesser slow loris(Nycticebus pygmaeus), Cellular respiration, BAT, NST

摘要： 倭蜂猴的最大非颤抖性产热较低，但占调节性产热的比例较高；褐色脂肪组织（BAT）重量也较其他灵长类大，产热活性也较强；肝脏线粒体氧化能力较低，与其具有较低的BMR和体温波动较大有关。倭蜂猴相对较低的NST和低水平的RMR对其夜行性和节约能量极为有利.

关键词: 倭蜂猴, 细胞呼吸, 褐色脂肪组织, 非颤抖性产热