ACTA THERIOLOGICA SINICA ›› 2020, Vol. 40 ›› Issue (6): 651-654.DOI: 10.16829/j.slxb.150388

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The first case of testicular seminoma pathologic diagnosis in giant panda

CHEN Mengzhu1, LIU Songrui 2, YUE Chanjuan 2, GENG Yi 1, SU Xiaoyan 2, CHEN Yaoyan 1, CHENG Zixuan 1   

  1. (1 Sichuan Agricultural University Collage of Veterinary Medicine, Wenjiang 611130, China)
    (2 Chengdu Research Base of Giant Panda Breeding, Sichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Sichuan Academy of Giant Panda, Chengdu 610000, China)
  • Online:2020-12-01 Published:2020-12-03


陈梦竹1 刘颂蕊2 岳婵娟2 耿 毅1 苏小艳2  陈垚焱1 程子瑄1   

  1. (1四川农业大学动物医学院,温江 611130)
    (2成都大熊猫繁育研究基地,四川省濒危野生动物保护生物学重点实验室,四川省大熊猫科学研究院,成都 610000)
  • 通讯作者: 刘颂蕊; 耿毅
  • 基金资助:


In China, the giant panda (Ailuropoda melanoleuca) is an endangered and rare national first-class protected animal with important research and ecological value. Tumor poses a serious threat to animal health. In this paper, a giant panda testicular tumor was diagnosed by macro and histopathologic examination, which aims to supplement the relevant data of giant panda tumor research, and also provides a reference for the diagnosis of giant panda tumor. Macro examination found that the testis was swollen about twice and the sheath was intact. The parenchyma was uniform in texture, grayish white with gray yellow caseous necrosis in the center. Histopathologically, the normal tissue structure of testis was lost and eroded by tumor cells. The tumor cells were similar to spermatogonia, round or polygonal, but with larger size, hyperchromatic cytoplasm and increased nuclear chromatin. Pathologic mitotic phases were found in tumor cells, and necrosis lesions with different sizes are distributed in tumor tissues. On the basis of macro and histopathologic examination results, the tumor was diagnosed as seminoma (also known as germ cell carcinoma), which is the first report of testicular seminoma in the giant panda.

Key words: Giant panda, Seminoma, Germ cell carcinoma, Histopathology

关键词: 大熊猫, 精原细胞瘤, 生殖细胞癌, 组织病理学