关键词: 高原鼠兔, 红细胞, Cb受体, 免疫复合物, 免疫功能

Abstract: The erythrocytic immune function of plateau pika(chotona curzoniae)was measuredand analyzed by the immune rosette assay of erythroeytic complement 3b(RBC—IC) receptors and immunocomplexes(RBC—IC)in this paper，The tested animals (26 young individuals，24 adults,and 14 old ones)are from the closedpopuiation domesticated in Northwest Plateau Institute of Biology，Academia Sinica，Xining，Qinghai．The resultsindicate that：(1)There are Cab receptors on red blood membrane in every age group ofthe pika，and all these receptors are able to adhere immune complex．(2)The erythrocyte(mean 8.5× 10)per individua1)is 2 125 times as more as the Ieucocyte (mean 4.0× 10) er individual)of the adult pika，so there are much more possible chance for the erythrocyte to adhere immunocomplexes．These facts obviously suggest that the crythroytcs play an important role in theimmunologleal system of the pika． There is no statisticaI difference between male and femaleindividuals in the same
age group of the pika．The difference ofred blood cell immune／unction also was eompared between differentage roups of the pika．The immune function of the pika gradually decrease with the increase of age．The erythrocytie immune adherence activities (RIrosette ratio)of different age roupsare respectively 43.35±9.11(the young)，34.71±8.18(the adult)and 28.25±7.06(the old)．
By comparing，red blood cell immune adherence activity of the pika is higher thanthose of human. hare and race．So Plateau pika woutd be an available species of laboratorialanimal for researchon red blood cell immunology．

Key words: Plateau pika(Ochottma curzoniae), Erythroeyte, C3b receptor, Immunocomplex, Immune function