关键词: 布氏田鼠, 高蛋白食物, 繁殖, 能量摄入, 产热能力

Abstract: The present study was designed to explore the effects of high protein diet and reproduction on food intake and thermogenesis in Brandt’s voles (Lasiopodomys brandtii). The adult female Brandt’s voles were divided into four groups,non-reproduction and control diet (NCon,17 7% of protein),non-reproduction and high protein diet (NHP,36 6% of protein), reproduction and control diet (RCon),and reproduction and high protein diet (RHP). Body mass,body composition,organ mass,food intake,resting metabolic rate (RMR),uncoupling protein 1 (UCP1)content in brown adipose tissue (BAT),and serum leptin and prolactin levels were measured. Body mass was decreased in voles fed high protein diet, but this effect was disappeared during pregnancy and lactation. Food intake,gross and digestible energy intake were decreased in non-reproductive voles fed high protein diet,but not during lactation in reproductive voles fed high protein diet.Digestibility was increased and serum leptin was decreased in both non-reproductive and reproductive voles fed high
protein diet. The kidney mass was increased and caecum mass was decreased in reproductive voles fed high protein diet. High protein diet had no effects on RMR,UCP1 content and serum prolactin levels in both non-reproductive and reproductive voles. The body mass,energy intake,RMR and serum prolactin were increased in reproductive voles compared with non-reproductive ones. Our results suggest that food quality can affect the energy metabolism in Brandt’s voles,and vole with different reproductive status showed different responses.

Key words: Brandt’s voles, Energy intake, High protein diet, Reproduction, Thermogenesis