An overabundance of plateau pika (Ochotona curzoniae)populations along with increased numbers of livestock was suspected to have caused degradation of the alpine meadow on the Tibetan Plateau． In April 2007,we conducted fertility control of plateau pika populations in Guoluo District, south of Qinghai Province, China．We investigated abundances of pika and bird species observed at the study sites during August and September 2007 and 2008 in order to evaluate the effects of quinestrol, levonorgestrel and EP -1 on plateau pikas, avian diversity and abundance． The results demonstrated that quinestrol reduced pika abundances significantly compared with control in the second year after delivering the baits, while bird diversity and species richness did not decline significantly Abundances of white-rumped snowfinch were significantly lower in quinestrol group compared with control, while abundances of rufous-necked snowfinch were significantly higher in quinestrol groups compared with EP -1 group．Quinestrol reduced pika population abundances, but had limited effects on avian diversity．Therefore, it was a potential approach that could be applied in the management of plateau pika on the Tibetan Plateau.